Kind: captions Language: en to Keep Us Alive the brain has evolved to look for signals of potential danger one of the most important is pain and as neuroscientist theanne Griffith is about to show me sometimes that can be a kind of Illusion as well so what is this this is a thermal Grill okay this is a machine that could give us some insight as to how pain works in your brain all right this is making me nervous already as I'm getting strapped in don't worry it's all an illusion actually okay and it's comprised of these different metal bars that are either set to a cold or warm temperature so why don't you go ahead and touch that first bar it's warm right and then the next bar cold mhm and then the next one warm you see so they're alternating cold warm cold warm now you want to see what happens when you put your hand down not necessarily go okay okay here we go ow right isn't that interesting yeah what is going on there it sort of feels cold at first but then then it gets this kind of burning sensation right yes very much so it feels super hot like I'm getting burnt so it's not 100% clear exactly how this is happening but what we think might be going on is that basically your brain is getting a little bit confused it's feeling cold and it's also feeling warmth and somehow it's interpreting these two signals as pain here's what neuroscientists think is is going on in your hands you have separate sensors for heat cold and pain normally when you touch something slightly cold both your cold and pain sensors are activated but the cold ones override the signals from the pain sensors telling your brain there's nothing to worry about unless In This Very unnatural scenario with the thermal Grill you happen to be touching something warm at the same time here the heat signals cancel out the cold ones leaving with just the pain ones activated telling your brain ouch so in that respect is pain real or is it just an illusion or a construct of the brain that's a really good question so noxious stimuli is is a real thing right if you stick your hand in boiling water that's an aversive stimulus the perception of a noxious stimuli is real M pain is more of a construct right and it can vary from Individual to individual pain is a construct of the brain how do we know that you touch a needle right and prick your finger we can draw the anatomy of what just happened we have very well-defined Pathways saying this is pain information we don't interpret it as pain until it hits your brain pain not unlike the experience of color is a construct of the mind but just because pain is in your brain doesn't make it any less critical for survival pain is a very important learning mechanism for children they learn what behaviors they can engage in that are safe and what behaviors will they should not engage in because they could cause them bodily harm and there's um uh different mutations that people can have in certain proteins that make them completely insensitive to pain and so kids do things like bite on their lips or on their fingers when they're very young and as they get older can engage in Risky Behavior so pain is extremely important for us to feel