Kind: captions Language: en [Music] cases of a deadly fungal infection are increasing and this might be caused by climate change that may sound like the plot of The Last of Us but fortunately this fungus called Candida Oris is not going to hijack your body and turn you into a zombie it is unusual though until now human bodies have been too warm for most fungi to grow and reproduce but experts think the fungi have evolved and are becoming more of a threat the functioning the environments are being exposed to climate change and as those fungi begin to adapt to higher temperatures we're going to lose the protection cases of candida Oris have been reported in over 28 States and are rapidly increasing year over year where there was a 44 increase in 2019 there was a 95 increase in 2021. that's what makes it concerning the fungus can lead to severe infection and can infect any body part including the blood it can survive on the skin and shed into the environment and contaminate surfaces this increase didn't just happen in areas where they've had sewers but it also occurred in areas that previously didn't have any transmission or areas that had not had any prior cases it's not just climate change fungi are adapting to and an Oris is just one of many organisms that's displaying increasing antimicrobial resistance antimicrobial resistance is when organisms like bacteria and fungi build a tolerance to drugs that in the previous years could have worked as treatment mutations develop in their genetic makeup that make it so the drugs no longer work candida Oris is challenging to treat because it's resistant to one of the three common anti-fungal treatments one class of drugs called echinocandins has been the most effective in treating the fungus although not in every case and a small percentage of candida Oris samples have been found to be resistant to that too we have not seen a lot of resistance to a kind of candidates yet so it's considered the first line treatment for infections but we are seeing more cases that have a kind of Canadian resistance or resistance to all three main classes candida Oris is so far mostly contained to Health Care settings in elderly patients people with weakened immune systems and patients that require invasive medical devices like catheters and breathing tubes this is really not a problem for the general public this is really a problem for people who are in the hospital for long periods of time in and out of the hospital very sick often in the ICU with devices but could this spread outside of healthcare facilities I think the concern when I emphasize that it's not happening today is whether this kind of in infection can spill out into the community I don't know if that's going to happen but the organism is changing rapidly and if that was to happen then we would have a much bigger problem than we have today we don't want people to think that spread is inevitable and you know be hopeless we want Health Care Providers and Health Care Facilities to stay motivated and realize that there's a lot that can be done to prevent spread foreign